Black Death Plague
In the Middle Ages, there was an event that brought terror to the whole of Europe, historically known as Black Death. This pandemic is also known as Black Death Plague, is a pandemic caused by the plague bacterium yersinia pestis.
Origin of Black Death Plague considered to be from ships trading from Asia, Africa to Europe. On the boats often stored rice, food – where the rats nest. The bubonic plague bacteria are spread by fleas that live on rats, which in turn infect humans. From the trading ships, the plague quickly spread to Europe.
At that time, the relatively backward medical system was not enough to fight this epidemic. In addition, Europe at that time was in constant war, people died everywhere, no one cared and managed, so it created conditions for the disease to spread quickly. The result is Black Death plague spread throughout Europe, spread to Asia, becoming the most terrible pandemic in the world.
With a total of 74-200 million deaths – more than half of Europe’s population, Black Death Plague It is still the deadliest and leading pandemic by far Top 10 scariest pandemics in world history.
Details:
- Time: 1346-1352
- The center of the pandemic: Europe, West Asia
- Bacteria: Yersinia pestis
- Number of dead: 75-200 million won

Spanish bird flu
Spanish flu was a global pandemic, occurred in 1918. The main cause of this terrible pandemic was the A/H1N1 virus, to this day mankind is still terrified of this strain of influenza (AH…N.. .).
In 1918, a new strain of influenza was discovered, derived from avian and seasonal influenza in humans, infecting pigs to create a new strain of influenza. This new strain of flu has the ability to spread as quickly as bird flu and have a high mortality rate like seasonal flu. Quickly, Spanish flu has spread globally, even to the most remote areas such as the islands of the Pacific Ocean or the Arctic. Part of the reason for the rapid spread of the pandemic is considered to be World War I, which sent too many soldiers and refugees from one country to another, leading to an uncontrolled spread. .
It is estimated that up to 5% of the world’s population has been infected with influenza A/H1N1 in Spanish flu. Of those infected, up to 100 million people have died. This is the first time the influenza A/H1N1 strain has been known to humans. To this day, A/H1N1 and viruses of the same family as A/H2N2, A/H5N1… are still scary viruses, even though humans have developed a preventive vaccine.
Details:
- Time: 1918-1920
- The center of the pandemic: Spanish
- Virus: A / H1N1
- Number of dead: 100 million

Hong Kong bird flu
The most recent flu epidemic was caused by new strains of influenza such as A/H5N1, A/H6N2 that were stopped by humans, but from the beginning of the pandemic influenza A strain in 1889 until 1968, the influenza A strain remained the same strain. deadly flu. Hong Kong bird flu broke out shortly after the 1957 Asian bird flu, with its epicenter in Hong Kong. Caused by influenza A/H3N2 strains also spread to poultry. From Hong Kong, the pandemic has spread worldwide, claiming the lives of 1 million people. With 1 million deaths, Hong Kong bird flu is the last name in Top 10 scariest pandemics in world history.
Details:
- Time: 1968-1969
- The center of the pandemic: Hong Kong, China
- Virus: A / H3N2
- Number of dead: 1 million

Roman smallpox epidemic
Recorded in history as the oldest pandemic in Top 10 scariest pandemics in world history, Roman smallpox epidemic boomed from 541-542 in the Roman Empire. Smallpox, also known as chickenpox, is caused by two bacteria, ariola major and variola minor. Patients with the disease have symptoms of nodules all over the body (looks like a bean ball). These are nodules caused by invading viruses, emerging under the blood vessels, gradually entering the bloodstream and causing the patient to die from internal bleeding. At that time, health was not yet developed, so smallpox spread very quickly, claiming the lives of 2 million Romans.
Details:
- Time: 541-542
- The center of the pandemic: Roman
- Bacteria: Ariola major and Variola minor
- Number of dead: 1,5 million

Translate Mexican Cocolitztli
Perhaps few people know, among Top 10 scariest pandemics in world historyThere was a pandemic that almost wiped out an entire country. That is translate Mexican Cocolitztli years 1545-1548. The pandemic took place in Mexico – a poor, backward Central American country at that time. This pandemic is considered to be caused by a strange indigenous virus called Cocolztli – a virus that causes dengue fever. Due to poor medical conditions, and isolated from the world by its remote location, Mexico has had a hard time fighting this pandemic.
Although it did not become a global pandemic, Translate Mexican cocolitztli killed about 5-15 million Mexicans, or about 80% of the country’s population. Shortly after, the pandemic, even if it was extinguished, returned and killed an additional 30-50% of the remaining population of Mexico. This was a pitiful loss that almost wiped out an entire country.
Details:
- Time: 1545-1548
- The center of the pandemic: Mexico
- Virus: Cocolitztli
- Number of dead: 5-15 million won

Asian bird flu
Asian bird flu The years 1889-1990 caused the most terrible disaster in the world. This is a bird flu, spread from birds to humans, so it is often called “avian flu”.
Year 1889, Asian bird flu outbreak, originating in Russia and then spreading to a series of other countries in Asia such as China, Japan, Korea… and then spreading globally. This is considered the first influenza A pandemic, even before the Spanish flu pandemic caused by the A/H1N1 virus.
Asian bird flu The year 1889-1890 is often confused with the Asian bird flu epidemic of 1957-1958, caused by the influenza A/H2N2 virus, the epicenter of the epidemic in China. However, Asian bird flu The epidemic in 1889-1890 had its origin in Russia, and up to 2 million people died, while the 1957 epidemic was only about 1 million people.
At the time of 1889-1890, medical experts still had many difficulties to find out the exact strain of the virus that caused the disease. They only knew that it was influenza A virus, and the study suggested that they could be H2 or H3. It was not until later, when the influenza A/H1N1 pandemic broke out, and studies on influenza A strains developed, that medical scientists found evidence, thereby being able to determine the cause of the disease. Asian bird flu is caused by viruses A/H2N2 and A/H3N8.
Details:
- Time: 1889-1890
- The center of the pandemic: Russia, Asia
- Virus: A/H2N2, A/H3N8
- Number of dead: 2 million

Indian cholera
Cholera used to be one of the deadliest diseases in the world.
Cholera is caused by unsanitary food and water. The bacterium Vibrio cholerae that causes cholera can be transmitted directly through unsanitary food or drink, or by flies, one of the most common vectors of cholera. Patients with cholera will experience diarrhea, gradually dying from exhaustion and dehydration.
Out of the seven outbreaks that turned into a pandemic, the first cholera pandemic, also known as Indian cholera is the scariest. The epidemic broke out from 1816-1826, claiming the lives of 15-23 million people. From India, the pandemic spread to Russia, Western Asia, Central Asia and Europe. Today, the medical industry has easily combated cholera, and eating cooked and drinking boiling water, clean hygiene, and avoiding flies in food are the recommendations of medical experts to prevent cholera.
Details:
- Time: 1816-1826
- The center of the pandemic: AN Djo
- Bacteria: Vibrio cholerae
- Number of dead: 15-23 million people

Russian translation
Among the seven times cholera outbreaks turned into a pandemic, Russian cholera Also known as the 3rd cholera epidemic, took place in 1852-1860. Through the trade route from India to Russia, cholera outbreak, then spread to Europe and North America. 1 million people worldwide have died in Russian cholera – greater than any other cholera epidemic excluding the first cholera epidemic in India.
Details:
- Time: 1852-1860
- The center of the pandemic: Russian
- Bacteria: Vibrio cholerae
- Number of dead: 1 million

HIV/AIDS epidemic
HIV / AIDS Surely the phrase is no longer strange to readers. Many readers may wonder why HIV / AIDS is considered a pandemic. Reality, HIV / AIDS has been called an “epidemic” by the WHO. HIV / AIDS are also caused by viruses, which infect and spread from person to person. The only difference is that HIV / AIDS did not break out in a scary way at a time, but quietly killed people through time, from 1986 to the present.
HIV / AIDS It is a disease caused by the HIV-1 virus. HIV-1 virus parasitizes the human body cells, causing the immunodeficiency syndrome, in the final stage, AIDS, the patient will die because the immune system is too weak, unable to fight common diseases. often.
HIV-1 virus is not spread through the air (such as influenza A virus, SARS) or surface contact (such as ncovid-2019) but is spread mainly through sex, blood and genetics. It is estimated that the highest transmission rate of HIV/AIDS epidemic is through sex, then blood. This explains why drug addicts who use needles are more likely to be infected HIV / AIDS very high.
Discovered in 1986, HIV / AIDS has killed 32 million people and still has no cure. This is considered the disease of the century – the most feared and deadly of all diseases. The reason is because the infected person HIV / AIDS will almost certainly die, in addition to the subjectivity in prevention, as well as the problem of drug and sex crimes that have become a global pain.
To this day, fighting with HIV / AIDS is still a difficult problem because this pandemic shows no sign of stopping. In 2018 alone, 770.000 people died from HIV / AIDS. Although this number has dropped significantly from the peak of the epidemic (in 2010 with 1,2 million deaths), it is still a high number, with a pandemic that has existed for more than 30 years. It is estimated that at present, there are still about 37,9 million people living with HIV / AIDS.
Thus, although not the top name in Top 10 scariest pandemics in world history, HIV/AIDS epidemic is still the number 1 horror, the “disease of the century” because of its destructive nature and no cure.
Details:
- Time: 1986-Present
- The center of the pandemic: Global
- Virus: HIV-1
- Number of dead: 32 million people

The Justinian Plague
Before the Black Death, Europe also suffered a terrible plague, that is Justinian plague. At that time, the plague was a common pandemic in Europe and the Mediterranean countries, re-emerged every few hundred years, but Europeans, due to limited knowledge, could not Find out the cause of this disease.
The Justinian Plague took place mainly in the Byzantine Empire, also known as the Eastern Roman Empire. Specifically, the first epidemic center was in the city of Justinian, then spread throughout Byzantine, Western Asia and some European countries such as France. The Justinian Plague causing the death of about 25-50 million people. The Justinian Plague often confused with the Black Death pandemic due to the same plague, occurring in Europe, but in fact Justinian plague took place eight centuries before the Black Death.
Details:
- Time: 541-542
- The center of the pandemic: Byzantine, Mediterranean
- Bacteria: Yersinia pestis
- Number of dead: 25-50 million people
